Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...

CHICAGO--(BUSINESS WIRE)--Celsis In Vitro Technologies Inc. (Celsis IVT), a division of the global life sciences company Celsis International plc, today announced the availability of Celsis InVitroCYP ...

It has recently been proposed that H2O2-dependent peroxidative formation of phenolic cross-links between cell-wall polymers serves as a mechanism for fixing the viscoelastically extended wall ...

The combination of translatable in-vitro and in-vivo assays, coupled with expertise in immunology and oncology helps facilitate the progression of novel oncology therapeutics from hit identification ...

BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced the publication of research describing the use of HEPATOPAC ® cultures with a targeted ...

One recent obstacle to drug delivery research is an observed weak correlation between in vitro and in vivo performance. When nanoparticles are applied intravenously, they face several obstacles that ...

Binding of a ligand to the native three-dimensional configuration of a protein increases protein stability, with a corresponding increase in the protein’s melting temperature. This indirect ...

Environmental Health Perspectives, Vol. 112, No. 6 (May, 2004), pp. 695-702 (8 pages) We evaluated and compared four in vitro assays to detect androgen agonists and antagonists in an international ...

In vitro assessment of the neurotoxic and neuroprotective effects of N-acetyl-L-cysteine (NAC) on the rat sciatic nerve fibers. Differential expression of genes associated with cell proliferation and ...

Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major influence on tumorigenesis. Thus, TAMs have gained increasing ...