Uncovering a secret room that a giant virus creates inside its host amoeba

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
Nature

Comparative study of codon substitution patterns in foot-and-mouth disease virus (serotype O)

We compared genetic variations in the VP1 gene of foot-and-mouth disease viruses (FMDVs) isolated since 2000 from various region of the world. We analyzed relative synonymous codon usage (RSCU) and ...
AZoLifeSciences on MSN

DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
JSTOR Daily

Estimating maximal microbial growth rates from cultures, metagenomes, and single cells via codon usage patterns

Maximal growth rate is a basic parameter of microbial lifestyle that varies over several orders of magnitude, with doubling times ranging from a matter of minutes to multiple days. Growth rates are ...
EurekAlert!

The secret room a giant virus creates inside its host amoeba

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...