For decades, scientists have been intrigued by tiny viruses whose genetic material can be read both forward and backward. New research begins to explain this puzzling property. In 1971, ...
RNA, or ribonucleic acid, is a essential biological molecule that plays a crucial role in various cellular processes. It is a polymeric molecule composed of nucleotides, each containing a ribose sugar ...
Researchers in China have developed a new method that allows them to insert long stretches of DNA into a genome. The process, named GRAND editing, is one of a handful of new systems aimed at using two ...
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...
Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a ...
The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...
Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...
Generation of Microgram Quantities of sgRNA in Less Than One Hour CRISPR is an acronym for Clustered Regularly Interspaced Palindromic Repeats, which are genomic loci found in many bacteria and ...
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