Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection ...

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it ...

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...

EPFL scientists have shown that a gene linked to a rare childhood disease is essential for regenerating intestinal stem cells after injury. Our intestines are constantly renewing themselves, replacing ...

The human gut is home to trillions of microbes that not only aid in digestion but also play a key role in shaping our immune system. These microbes communicate with the body by releasing a range of ...

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...