A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

In mouse models, scientists at Cincinnati Children's and Ulm University in Germany show that transferring microbiota from young mice to older mice rejuvenates intestinal stem cell function and speeds ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to the stem cells responsible for maintaining and healing the intestine. The ...

A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it boosted regeneration, reduced inflammation, and improved nutrient absorption, ...

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal ...

Eating is one of life’s few constants: If you’re not eating right now, you’ll certainly be eating something within a few hours. But when and how often we should eat is still not fully understood.

A diet rich in the amino acid cysteine may have rejuvenating effects in the small intestine, according to a new study from MIT. This amino acid, the researchers discovered, can turn on an immune ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

The Center for Intestinal Systems (CIS) is a nationwide collaborative initiative launched by the Imperial Organoid Facility on 12th January 2026 that will build a unique infrastructure for in-vitro ...