A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.

A study has sampled single live cancer cells and measured the fatty lipid compounds inside them. The team saw how those cells transformed in response to changes in their environment. Imagine being ...

In addition to providing energy, lipids are also essential building blocks of our cell membranes. However, despite their ...

New study demonstrates that one type of lipid is so critical for immune evasion that certain cancers cannot proliferate without them. Modulating intake of dietary lipids could open up an avenue for ...

Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows. This lipid abundance asymmetry is enabled by the unique properties of ...

Therapies that target the utilization of fat by tumors and activate a type of cell death dependent on fat molecules may be a ...

A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that ...

The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the degradation of such materials is called LC3-associated phagocytosis (LAP). This ...

Lipids in cell membranes regulate the activity of a cancer-linked protein, cell biologists at RIKEN have discovered. This finding, published in the journal eLife, could pave the way for novel ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...