Patients with first-episode MDD showed lower effective and functional connectivity between the anterior cingulate cortex and frontal regions.

Mood symptoms alone do not account for the extent of disability associated with MDD. 12 Cognitive impairment, 1 of the 9 core symptoms of MDD (see Table 1), is significantly associated with impaired ...

In some ways, MDD can make work more difficult. It may create added stress and make your responsibilities feel more challenging. Hard work, deadlines, and an unfriendly environment may be a struggle.

Neumora Therapeutics, Inc. (NMRA) is gearing up to report results from one of its phase 3 studies, which is using its drug Navacaprant for the treatment of patients with major depressive disorder (MDD ...

Rejoyn is expected to be available for download from app stores for iOS and Android in the second half of 2024. The Food and Drug Administration (FDA) has cleared Rejoyn ™ for the treatment of major ...

In addition to ADHD and MDD, Axsome also is investigating Sunosi as a treatment for binge eating disorder and excessive sleepiness associated with shift work disorder. Given its novel mechanism of ...

Remission (MADRS total score ≤10) was seen in 65% of patients treated with lumateperone in combination with an oral antidepressant, at 6 months. The Food and Drug Administration (FDA) has approved ...