A study spanning 20 years helps nail down the timing of biomarker changes that occur in the period between normal cognition and a diagnosis of sporadic Alzheimer's disease (AD), something that hasn't ...

Including nearly 20,000 participants, the largest study on amyloid prevalence to date estimates that a third of cognitively normal people older than 70 have amyloid building up in their brains.

A large number of studies over the past 20 years have quantified tau protein in the cerebrospinal fluid of people with Alzheimer’s disease, consistently finding elevated levels of tau in AD—such that ...