The primary goal of fixation is to arrest the autolysis and putrefaction of tissues with the goal of stabilizing the morphological structure and biochemical relationships between constituent proteins ...

Formalin-fixed paraffin-embedded (FFPE) tissues have long served as invaluable resources in biomedical research, particularly in clinical and translational studies. Despite the inherent challenges ...

A prospective, non-interventional study among patients diagnosed with locally advanced or metastatic non–small-cell lung cancer to assess the adherence to oral antineoplastic therapy from data ...

Next-generation sequencing (NGS) has transformed genomic research and clinical diagnostics by enabling rapid, high-throughput analysis of genetic material. The application of NGS to formalin-fixed ...

Scientists from Spain have recently compared the efficacy of the quantitative polymerase chain reaction (qPCR) method and immunohistochemistry in detecting severe acute respiratory syndrome ...

Formalin-fixed paraffin-embedded (FFPE) tissues are the most widely used clinical sample types in histology and molecular diagnosis. However, due to RNA degradation and protein crosslinking, FFPE ...

Assessment of tumour infiltrating subpopulations and pathological complete response using multiplex immunohistochemistry and digital pathology in early HER2+ breast cancer. This is an ASCO Meeting ...