Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...

A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

Metacaspases, ancestral homologues of the caspase family, are pivotal cysteine proteases found in a wide range of unicellular organisms, including yeasts, algae, and phytoplankton. These enzymes ...

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved in programmed cell death (PCD) play a key role in normal tissue renewal and ...

Researchers use a simplified model of a protein network to explain how apoptosis is regulated, whose malfunction is linked to cancer and neurodegenerative diseases. Joint press release by the ...