Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...

What is Photoactivated Localization Microscopy? Photoactivated Localization Microscopy (PALM) is a super-resolution imaging technique that allows for the visualization of biological structures at the ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

In a recent article published in Nature Communications, researchers introduced NanoPlex, a novel strategy designed to overcome limitations in fluorescence microscopy by utilizing engineered secondary ...

What is Single-Molecule Localization Microscopy? Single-molecule localization microscopy (SMLM) is a super-resolution imaging technique that enables the visualization of biological structures and ...

News Medical talks to Samuel Penwell and Winfried Wiegraebe about how the Vutara VXL enables robust, high-throughput 3D super-resolution via single-molecule localization, pairing bi-plane detection ...

Accumulation of amyloid-beta (A-beta) peptides inhibiting normal brain function is a characteristic aspect of neurodegenerative disease, but how A-beta comes together and breaks apart as it does the ...

Processes in the human body are shaped by the interaction of various biomolecules, such as proteins and DNA. These processes take place in a range of often just a few nanometers. They can therefore no ...

Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.