A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators. The ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

Deciphering the spatial, temporal and chemical complexity of RNA molecules in living systems is key to understanding gene regulation at the molecular level. Recent advances in imaging, molecular ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...

Once considered passive messengers of genetic information, RNA molecules are now understood to play an active and dynamic role in gene regulation, modulated by a rich layer of chemical modifications ...

RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...

Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called SegPore that enhances the accuracy of RNA modification detection from direct RNA ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...