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49ers, Colts and NFL

NFL experts predict winner of Colts vs. 49ers Week 16 game

All three members of ESPN are picking the 49ers as well. ESPN's Football Power Index simulation model has the 49ers winning this game 61.2% of the time and doing so by an average of 4.3 points. The Indianapolis Colts are at home in Week 16 for a Monday Night matchup with the San Francisco 49ers.

· 3h · on MSN

Colts on SI Staff Divided with Predictions in Matchup vs. 49ers

· 14h · on MSN

NFL predictions: Playoff implications for 49ers vs. Colts on Monday Night Football from proven model

· 16h

Colts bold predictions for Week 16 Monday Night Football clash vs. 49ers

The Indianapolis Colts desperately need a win in Week 16.

NFL · 1d

49ers vs. Colts preview | Week 16

· 19h

Key 49ers defensive reinforcements nearing return ahead of Week 16 vs. Colts

Seahawks, 49ers share driver’s seat for NFC’s top seed

Digest more

· 11h · on MSN

49ers NFC playoff watch: Why tonight’s Rams-Seahawks game has big implications

The San Francisco 49ers have a lot riding on Thursday night’s game between the Los Angeles Rams and Seattle Seahawks.

· 4h

Seahawks, 49ers share driver’s seat for NFC’s top seed; Rams’ chances plummet

Marin Independent Journal · 2h

Planting seeds: 49ers’ win-out plan is bolstered by Seahawks’ win over Rams

· 11h

How to watch Rams vs Seahawks Thursday Night Football tonight

The Seattle Seahawks will host the Los Angeles Rams for Thursday Night Football.

· 1d

The stakes are high as the Seahawks and Rams square off in a game with division title implications

· 7h

Seahawks in play-offs with overtime win over Rams

· 9h

Seahawks proved they’re team to beat in the NFC and whole lot more

Los Angeles Rams quarterback Matthew Stafford appeared to solidify himself as the MVP favorite, fileting a surprisingly susceptible defense.

· 9h

Rams vs. Seahawks Highlights: Seattle Wins in Walk-off Fashion

· 18h

2025 NFL Week 16 Picks: Best Bets for Every Game — Will's Wagers

What channel is 49ers vs Titans NFL game today? Start time, schedule, where to watch, streaming

The NFL season continues in Week 15 when the San Francisco 49ers host the Tennessee Titans on Sunday. Start time, how to watch, stream and NFL TV schedule.

20h

How tonight’s Rams-Seahawks game will dictate 49ers’ playoff path

The 49ers’ playoff picture will be dramatically impacted by tonight’s NFC West battle in Seattle between the Seahawks and the Rams.

13hon MSN

49ers' Ricky Pearsall's status uncertain for Colts game because of knee and ankle injuries

San Francisco 49ers wide receiver Ricky Pearsall has missed the team's first practice of the week due to knee and ankle injuries.

Niners Wire

49ers vs. Titans highlights: SF extends win streak to 4 games

The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.

49ers Webzone

49ers’ Brock Purdy sends clear message on his game-day mindset

Brock Purdy opens up about his game-day philosophy as San Francisco surges toward the playoffs after a big win over the Titans.

49ers report card vs. Titans: Pass game looks easy for Purdy

SANTA CLARA – Here is how the 49ers (10-4) graded in Sunday’s 37-24 home win over the Tennessee Titans (2-11):

4don MSN

Titans vs 49ers box score, player stats, game stats, score summary

See the Titans vs 49ers game stats from the 37-24 loss on Dec. 14, 2025, including match player stats and team stats.

17hon MSN

Colts get major update on QB Anthony Richardson ahead of 49ers game

The Indianapolis Colts get a crucial update on the status of former first-round pick quarterback Anthony Richardson. The post Colts Get Major Update on QB Anthony Richardson Ahead of 49ers Game appeared first on Heavy Sports.