The direct observation and quantification of G-quadruplex structures formed from DNA in human cells during the cell cycle demonstrate the biological importance of these structures and point towards ...

Extensive structural and biophysical evidence confirms that certain G-rich DNA (and RNA) sequences can fold into non-canonical secondary structures, called G-quadruplexes. G-quadruplex structures ...

Like the aglets at the end of your shoelaces, protein-and-DNA assemblies known as telomeres protect the ends of your chromosomes from fraying. In work with potential implications for the development ...

This image is based on an x-ray crystal structure of a G-quadruplex formed from the DNA sequence found in human genomes. This image is based on an x-ray crystal structure of a G-quadruplex formed from ...

The world’s most famous molecule – the DNA double helix – sometimes doubles up again. Researchers have now found this quadruple-stranded form in healthy human cells for the first time. Four-stranded ...

DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...

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