With a rate of mutation 35 percent higher than random chance, this previously unknown weakness could be a major vector for ...

Cancer isn't just about broken genes-it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off neighborhoods from essential services.

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...