A pioneering genetic treatment is saving lives where chemotherapy failed, offering new hope for children and adults with aggressive leukemia. This world-first therapy has kept patients disease-free ...

There may be an evolutionary thread linking big brains, long lifespans and immune-system genes in mammals, a new study finds. An organism’s lifespan depends partly on its genes, but scientists have ...

Scientists at UCL and GOSH have used groundbreaking base-edited CAR‑T cell therapy — BE‑CAR7 — to treat aggressive T‑cell ...

Sequencing diverse populations revealed over 41,000 transcripts missing in Eurocentric references, exposing ancestry bias ...

Younger donor age (18-35) is crucial for stem cell transplant success and patient survival; superseding related sibling matches and older donor paradigms.

T therapy has helped previously untreatable for T-cell acute lymphoblastic leukemia patients achieve remission, with 82% ...

Seq, a CRISPR-based method that enriches ultra-rare tumor DNA in blood by removing background wild-type DNA before sequencing ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

New research is challenging one of medicine’s oldest assumptions: that cancer must be attacked to be cured. By treating glioblastoma patients with a simple combination of resveratrol and copper, the ...

The immunotherapies used to treat melanoma now include well-established drugs such as Keytruda (pembrolizumab) and Opdivo (nivolumab) and newer ones such as Amtagvi (lifileucel), which uses T cells ...

A therapy that would once have been considered a feat of science fiction has reversed aggressive and incurable blood cancers ...

MUTE-Seq is a new liquid-biopsy method powered by an engineered ultra-precise CRISPR enzyme, FnCas9-AF2, which can ...