A week ago, Philip Rivers shocked the NFL when he decided to work out with the Colts amid injuries to quarterbacks Daniel ...

San Francisco 49ers quarterback Brock Purdy (13) runs the ball past Tennessee Titans linebacker Cedric Gray, left, during the ...

The 49ers square off against the Colts and their newly un-retired quarterback on Monday Night Football in Week 16.

Kyle Shanahan explains the 49ers' pregame roster moves and what Jordan Watkins must do to earn more playing time this season.

The 49ers received some positive news about left guard Spencer Burford, and are hopeful to get several players back at ...

The San Francisco 49ers are trending the right way from a health perspective entering a Week 16 showdown with the Indianapolis Colts.

San Francisco 49ers coach Kyle Shanahan has shared some concerning news following the team's win over the Tennessee Titans.

The San Francisco 49ers are headed to Indianapolis for a Week 16 matchup against the Colts, and they now officially know who ...

On Sunday, the 49ers beat Tennessee 37-24, and Aiyuk's replacement, Ricky Pearsall, had six catches for 96 yards. So before ...

San Francisco 49ers quarterback Brock Purdy looked like a basketball player with an impressive touchdown pass on Sunday.

Brock Purdy delivered a signature moment in Sunday's win over the Titans, using his legs to key a 95-yard scoring drive.

The San Francisco 49ers beat the Tennessee Titans on Sunday, and in the locker room they celebrated their coach's birthday.