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  1. Major depressive disorder - Wikipedia

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [10] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or …

  2. Depression (major depressive disorder) - Symptoms and causes

    Oct 14, 2022 · Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble …

  3. Clinical Depression (Major Depressive Disorder): Symptoms

    Nov 30, 2022 · Clinical depression, also known as major depressive disorder (MDD), is a mental health condition that causes a persistently low or depressed mood and a loss of interest in activities that …

  4. Major Depressive Disorder | National Alliance on Mental Illness ... - NAMI

    When more severe symptoms like lack of energy and hopelessness develop in multiple areas of a person’s life along with persistent sadness over at least two weeks, they may be experiencing a …

  5. Major Depressive Disorder (MDD) - MentalHealth.com

    Aug 7, 2025 · Major Depressive Disorder (MDD) is a common but serious mental health condition. This is more than just feeling sad or going through a rough patch; it’s a medical illness that causes a …

  6. Depression - National Institute of Mental Health (NIMH)

    Depression (also called major depressive disorder or clinical depression) is different. It can cause severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or …

  7. Psychiatry.org - What Is Depression?

    Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Fortunately, it is also treatable.

  8. Major Depressive Disorder: Symptoms, Causes, Treatment

    Dec 11, 2025 · What Is Major Depressive Disorder? Major depressive disorder (MDD) is a serious mood disorder causing mild to severe symptoms that persist for two weeks or longer and affect daily life.

  9. Major depression: MedlinePlus Medical Encyclopedia

    Apr 19, 2025 · Depression is feeling sad, blue, unhappy, or down in the dumps. Most people feel this way once in a while. Major depression is a mood disorder. It occurs when feelings of sadness, loss, …

  10. Major depressive disorder (also known as major depression) is one of the most common mental disorders in the United States. It can seriously impact every aspect of a person’s life—affecting how …